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Distinct effects of tubulin isotype mutations on neurite growth in Caenorhabditis elegans
Tubulins, the building block of microtubules (MTs), play a critical role in both supporting and regulating neurite growth. Eukaryotic genomes contain multiple tubulin isotypes, and their missense mutations cause a range of neurodevelopmental defects. Using the Caenorhabditis elegans touch receptor n...
Autores principales: | Zheng, Chaogu, Diaz-Cuadros, Margarete, Nguyen, Ken C. Q., Hall, David H., Chalfie, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638583/ https://www.ncbi.nlm.nih.gov/pubmed/28835377 http://dx.doi.org/10.1091/mbc.E17-06-0424 |
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