Cargando…
Monoubiquitination of syntaxin 3 leads to retrieval from the basolateral plasma membrane and facilitates cargo recruitment to exosomes
Syntaxin 3 (Stx3), a SNARE protein located and functioning at the apical plasma membrane of epithelial cells, is required for epithelial polarity. A fraction of Stx3 is localized to late endosomes/lysosomes, although how it traffics there and its function in these organelles is unknown. Here we repo...
Autores principales: | Giovannone, Adrian J., Reales, Elena, Bhattaram, Pallavi, Fraile-Ramos, Alberto, Weimbs, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638587/ https://www.ncbi.nlm.nih.gov/pubmed/28814500 http://dx.doi.org/10.1091/mbc.E17-07-0461 |
Ejemplares similares
-
The H(abc) domain of syntaxin 3 is a ubiquitin binding domain
por: Giovannone, Adrian J., et al.
Publicado: (2020) -
Apical targeting of syntaxin 3 is essential for epithelial cell polarity
por: Sharma, Nikunj, et al.
Publicado: (2006) -
Basolateral Sorting of Syntaxin 4 Is Dependent on Its N-terminal Domain and the AP1B Clathrin Adaptor, and Required for the Epithelial Cell Polarity
por: Reales, Elena, et al.
Publicado: (2011) -
Syntaxin 16 is a master recruitment factor for cytokinesis
por: Neto, Hélia, et al.
Publicado: (2013) -
Iterative sorting of apical and basolateral cargo in Madin–Darby canine kidney cells
por: Treyer, Aleksandr, et al.
Publicado: (2016)