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KDM6A addiction of cervical carcinoma cell lines is triggered by E7 and mediated by p21(CIP1) suppression of replication stress
Expression of E7 proteins encoded by carcinogenic, high-risk human papillomaviruses (HPVs) triggers increased expression of the histone H3 lysine 27 demethylase KDM6A. KDM6A expression is necessary for survival of high-risk HPV E7 expressing cells, including several cervical cancer lines. Here we sh...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638616/ https://www.ncbi.nlm.nih.gov/pubmed/28968467 http://dx.doi.org/10.1371/journal.ppat.1006661 |