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EBF1 binds to EBNA2 and promotes the assembly of EBNA2 chromatin complexes in B cells
Epstein-Barr virus (EBV) infection converts resting human B cells into permanently proliferating lymphoblastoid cell lines (LCLs). The Epstein-Barr virus nuclear antigen 2 (EBNA2) plays a key role in this process. It preferentially binds to B cell enhancers and establishes a specific viral and cellu...
Autores principales: | Glaser, Laura V., Rieger, Simone, Thumann, Sybille, Beer, Sophie, Kuklik-Roos, Cornelia, Martin, Dietmar E., Maier, Kerstin C., Harth-Hertle, Marie L., Grüning, Björn, Backofen, Rolf, Krebs, Stefan, Blum, Helmut, Zimmer, Ralf, Erhard, Florian, Kempkes, Bettina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638620/ https://www.ncbi.nlm.nih.gov/pubmed/28968461 http://dx.doi.org/10.1371/journal.ppat.1006664 |
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