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Genetic economy in picornaviruses: Foot-and-mouth disease virus replication exploits alternative precursor cleavage pathways

The RNA genomes of picornaviruses are translated into single polyproteins which are subsequently cleaved into structural and non-structural protein products. For genetic economy, proteins and processing intermediates have evolved to perform distinct functions. The picornavirus precursor protein, P3,...

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Detalles Bibliográficos
Autores principales: Herod, Morgan R., Gold, Sarah, Lasecka-Dykes, Lidia, Wright, Caroline, Ward, Joseph C., McLean, Thomas C., Forrest, Sophie, Jackson, Terry, Tuthill, Tobias J., Rowlands, David J., Stonehouse, Nicola J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638621/
https://www.ncbi.nlm.nih.gov/pubmed/28968463
http://dx.doi.org/10.1371/journal.ppat.1006666