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Extracellular matrix stiffness and cell contractility control RNA localization to promote cell migration

Numerous RNAs are enriched within cellular protrusions, but the underlying mechanisms are largely unknown. We had shown that the APC (adenomatous polyposis coli) protein controls localization of some RNAs at protrusions. Here, using protrusion-isolation schemes and RNA-Seq, we find that RNAs localiz...

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Detalles Bibliográficos
Autores principales:	Wang, Tianhong, Hamilla, Susan, Cam, Maggie, Aranda-Espinoza, Helim, Mili, Stavroula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638855/ https://www.ncbi.nlm.nih.gov/pubmed/29026081 http://dx.doi.org/10.1038/s41467-017-00884-y

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