Cargando…
Bortezomib promotes KHSV and EBV lytic cycle by activating JNK and autophagy
KSHV and EBV are gammaherpesviruses strictly linked to human cancers. Even if the majority of cancer cells harbor a latent infection, the few cells that undergo viral replication may contribute to the pathogenesis and maintenance of the virus-associated malignancies. Cytotoxic drugs used for the the...
Autores principales: | Granato, Marisa, Romeo, Maria Anele, Tiano, Mariangela Sara, Santarelli, Roberta, Gonnella, Roberta, Gilardini Montani, Maria Saveria, Faggioni, Alberto, Cirone, Mara |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638868/ https://www.ncbi.nlm.nih.gov/pubmed/29026157 http://dx.doi.org/10.1038/s41598-017-13533-7 |
Ejemplares similares
-
Viral Infection and Autophagy Dysregulation: The Case of HHV-6, EBV and KSHV
por: Romeo, Maria Anele, et al.
Publicado: (2020) -
Quercetin Interrupts the Positive Feedback Loop Between STAT3 and IL-6, Promotes Autophagy, and Reduces ROS, Preventing EBV-Driven B Cell Immortalization
por: Granato, Marisa, et al.
Publicado: (2019) -
KSHV infection skews macrophage polarisation towards M2-like/TAM and activates Ire1 α-XBP1 axis up-regulating pro-tumorigenic cytokine release and PD-L1 expression
por: Gilardini Montani, Maria Saveria, et al.
Publicado: (2020) -
IRE1 Alpha/XBP1 Axis Sustains Primary Effusion Lymphoma Cell Survival by Promoting Cytokine Release and STAT3 Activation
por: Gonnella, Roberta, et al.
Publicado: (2021) -
Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death
por: Granato, Marisa, et al.
Publicado: (2017)