Growth hormone secretagogues hexarelin and JMV2894 protect skeletal muscle from mitochondrial damages in a rat model of cisplatin-induced cachexia

Chemotherapy can cause cachexia, which consists of weight loss associated with muscle atrophy. The exact mechanisms underlying this skeletal muscle toxicity are largely unknown and co-therapies to attenuate chemotherapy-induced side effects are lacking. By using a rat model of cisplatin-induced cach...

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Detalles Bibliográficos
Autores principales: Sirago, Giuseppe, Conte, Elena, Fracasso, Flavio, Cormio, Antonella, Fehrentz, Jean-Alain, Martinez, Jean, Musicco, Clara, Camerino, Giulia Maria, Fonzino, Adriano, Rizzi, Laura, Torsello, Antonio, Lezza, Angela Maria Serena, Liantonio, Antonella, Cantatore, Palmiro, Pesce, Vito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638899/
https://www.ncbi.nlm.nih.gov/pubmed/29026190
http://dx.doi.org/10.1038/s41598-017-13504-y

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