Deciphering TAL effectors for 5-methylcytosine and 5-hydroxymethylcytosine recognition

DNA recognition by transcription activator-like effector (TALE) proteins is mediated by tandem repeats that specify nucleotides through repeat-variable diresidues. These repeat-variable diresidues form direct and sequence-specific contacts to DNA bases; hence, TALE–DNA interaction is sensitive to DN...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yuan, Liu, Lulu, Guo, Shengjie, Song, Jinghui, Zhu, Chenxu, Yue, Zongwei, Wei, Wensheng, Yi, Chengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638953/
https://www.ncbi.nlm.nih.gov/pubmed/29026078
http://dx.doi.org/10.1038/s41467-017-00860-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638953/
https://www.ncbi.nlm.nih.gov/pubmed/29026078
http://dx.doi.org/10.1038/s41467-017-00860-6

Ejemplares similares