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Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report

Radiotherapy is one of the standard treatments for medulloblastoma. However, therapeutic central nervous system irradiation in children may carry delayed side effects, such as radiation-induced tumor and vasculopathy. Here, we report the first case of coexisting meningioma and moyamoya syndrome, pre...

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Autores principales: Han, Ji Yeon, Choi, Jung Won, Wang, Kyu-Chang, Phi, Ji Hoon, Lee, Ji Yeoun, Chae, Jong-Hee, Park, Sung-Hye, Cheon, Jung-Eun, Kim, Seung-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639076/
https://www.ncbi.nlm.nih.gov/pubmed/28960048
http://dx.doi.org/10.3346/jkms.2017.32.11.1896
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author Han, Ji Yeon
Choi, Jung Won
Wang, Kyu-Chang
Phi, Ji Hoon
Lee, Ji Yeoun
Chae, Jong-Hee
Park, Sung-Hye
Cheon, Jung-Eun
Kim, Seung-Ki
author_facet Han, Ji Yeon
Choi, Jung Won
Wang, Kyu-Chang
Phi, Ji Hoon
Lee, Ji Yeoun
Chae, Jong-Hee
Park, Sung-Hye
Cheon, Jung-Eun
Kim, Seung-Ki
author_sort Han, Ji Yeon
collection PubMed
description Radiotherapy is one of the standard treatments for medulloblastoma. However, therapeutic central nervous system irradiation in children may carry delayed side effects, such as radiation-induced tumor and vasculopathy. Here, we report the first case of coexisting meningioma and moyamoya syndrome, presenting 10 years after radiotherapy for medulloblastoma. A 13-year-old boy presented with an enhancing mass at the cerebral falx on magnetic resonance imaging (MRI) after surgery, radiotherapy (30.6 Gy craniospinal axis, 19.8 Gy posterior fossa) and chemotherapy against medulloblastoma 10 years ago, previously. The second tumor was meningioma. On postoperative day 5, he complained of right-sided motor weakness, motor dysphasia, dysarthria, and dysphagia. MRI revealed acute cerebral infarction in the left frontal lobe and both basal ganglia. MR and cerebral angiography confirmed underlying moyamoya syndrome. Four months after the meningioma surgery, the patient presented with headaches, dysarthria, and dizziness. Indirect bypass surgery was performed. He has been free from headaches since one month after the surgery. For patients who received radiotherapy for medulloblastoma at a young age, clinicians should consider the possibility of the coexistence of several complications. Careful follow up for development of secondary tumor and delayed vasculopathy is required.
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spelling pubmed-56390762017-11-01 Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report Han, Ji Yeon Choi, Jung Won Wang, Kyu-Chang Phi, Ji Hoon Lee, Ji Yeoun Chae, Jong-Hee Park, Sung-Hye Cheon, Jung-Eun Kim, Seung-Ki J Korean Med Sci Case Report Radiotherapy is one of the standard treatments for medulloblastoma. However, therapeutic central nervous system irradiation in children may carry delayed side effects, such as radiation-induced tumor and vasculopathy. Here, we report the first case of coexisting meningioma and moyamoya syndrome, presenting 10 years after radiotherapy for medulloblastoma. A 13-year-old boy presented with an enhancing mass at the cerebral falx on magnetic resonance imaging (MRI) after surgery, radiotherapy (30.6 Gy craniospinal axis, 19.8 Gy posterior fossa) and chemotherapy against medulloblastoma 10 years ago, previously. The second tumor was meningioma. On postoperative day 5, he complained of right-sided motor weakness, motor dysphasia, dysarthria, and dysphagia. MRI revealed acute cerebral infarction in the left frontal lobe and both basal ganglia. MR and cerebral angiography confirmed underlying moyamoya syndrome. Four months after the meningioma surgery, the patient presented with headaches, dysarthria, and dizziness. Indirect bypass surgery was performed. He has been free from headaches since one month after the surgery. For patients who received radiotherapy for medulloblastoma at a young age, clinicians should consider the possibility of the coexistence of several complications. Careful follow up for development of secondary tumor and delayed vasculopathy is required. The Korean Academy of Medical Sciences 2017-11 2017-09-01 /pmc/articles/PMC5639076/ /pubmed/28960048 http://dx.doi.org/10.3346/jkms.2017.32.11.1896 Text en © 2017 The Korean Academy of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Han, Ji Yeon
Choi, Jung Won
Wang, Kyu-Chang
Phi, Ji Hoon
Lee, Ji Yeoun
Chae, Jong-Hee
Park, Sung-Hye
Cheon, Jung-Eun
Kim, Seung-Ki
Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report
title Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report
title_full Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report
title_fullStr Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report
title_full_unstemmed Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report
title_short Coexistence of Radiation-Induced Meningioma and Moyamoya Syndrome 10 Years after Irradiation against Medulloblastoma: a Case Report
title_sort coexistence of radiation-induced meningioma and moyamoya syndrome 10 years after irradiation against medulloblastoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639076/
https://www.ncbi.nlm.nih.gov/pubmed/28960048
http://dx.doi.org/10.3346/jkms.2017.32.11.1896
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