Blockage of the Epithelial-to-Mesenchymal Transition Is Required for Embryonic Stem Cell Derivation

Pluripotent cells emanate from the inner cell mass (ICM) of the blastocyst and when cultivated under optimal conditions immortalize as embryonic stem cells (ESCs). The fundamental mechanism underlying ESC derivation has, however, remained elusive. Recently, we have devised a highly efficient approac...

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Detalles Bibliográficos
Autores principales: Totonchi, Mehdi, Hassani, Seyedeh-Nafiseh, Sharifi-Zarchi, Ali, Tapia, Natalia, Adachi, Kenjiro, Arand, Julia, Greber, Boris, Sabour, Davood, Araúzo-Bravo, Marcos J., Walter, Jörn, Pakzad, Mohammad, Gourabi, Hamid, Schöler, Hans R., Baharvand, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639184/
https://www.ncbi.nlm.nih.gov/pubmed/28919260
http://dx.doi.org/10.1016/j.stemcr.2017.08.006

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