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Top-Down Inhibition of BMP Signaling Enables Robust Induction of hPSCs Into Neural Crest in Fully Defined, Xeno-free Conditions

Defects in neural crest development have been implicated in many human disorders, but information about human neural crest formation mostly depends on extrapolation from model organisms. Human pluripotent stem cells (hPSCs) can be differentiated into in vitro counterparts of the neural crest, and so...

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Detalles Bibliográficos
Autores principales:	Hackland, James O.S., Frith, Tom J.R., Thompson, Oliver, Marin Navarro, Ana, Garcia-Castro, Martin I., Unger, Christian, Andrews, Peter W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639211/ https://www.ncbi.nlm.nih.gov/pubmed/28919261 http://dx.doi.org/10.1016/j.stemcr.2017.08.008

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