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Modulation of defensive reactivity by GLRB allelic variation: converging evidence from an intermediate phenotype approach
Representing a phylogenetically old and very basic mechanism of inhibitory neurotransmission, glycine receptors have been implicated in the modulation of behavioral components underlying defensive responding toward threat. As one of the first findings being confirmed by genome-wide association studi...
Autores principales: | Lueken, U, Kuhn, M, Yang, Y, Straube, B, Kircher, T, Wittchen, H-U, Pfleiderer, B, Arolt, V, Wittmann, A, Ströhle, A, Weber, H, Reif, A, Domschke, K, Deckert, J, Lonsdorf, T B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639239/ https://www.ncbi.nlm.nih.gov/pubmed/28872638 http://dx.doi.org/10.1038/tp.2017.186 |
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