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In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma
Generation of hematopoietic stem cells (HSCs) from pluripotent stem cells (PSCs) could potentially provide unlimited HSCs for clinical transplantation, a curative treatment for numerous blood diseases. However, to date, bona fide HSC generation has been largely unsuccessful in vitro. We have previou...
Autores principales: | Tsukada, Masao, Ota, Yasunori, Wilkinson, Adam C., Becker, Hans J., Osato, Motomi, Nakauchi, Hiromitsu, Yamazaki, Satoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639260/ https://www.ncbi.nlm.nih.gov/pubmed/28943250 http://dx.doi.org/10.1016/j.stemcr.2017.08.010 |
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