Cargando…
IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells
Human pluripotent stem cell (hPSC)-derived mesencephalic dopaminergic (mesDA) neurons can relieve motor deficits in animal models of Parkinson's disease (PD). Clinical translation of differentiation protocols requires standardization of production procedures, and surface-marker-based cell sorti...
Autores principales: | Lehnen, Daniela, Barral, Serena, Cardoso, Tiago, Grealish, Shane, Heuer, Andreas, Smiyakin, Andrej, Kirkeby, Agnete, Kollet, Jutta, Cremer, Harold, Parmar, Malin, Bosio, Andreas, Knöbel, Sebastian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639383/ https://www.ncbi.nlm.nih.gov/pubmed/28943253 http://dx.doi.org/10.1016/j.stemcr.2017.08.016 |
Ejemplares similares
-
Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons
por: Grealish, Shane, et al.
Publicado: (2015) -
hESC-derived neural progenitors prevent xenograft rejection through neonatal desensitisation
por: Heuer, Andreas, et al.
Publicado: (2016) -
Generating regionalized neuronal cells from pluripotency, a step-by-step protocol
por: Kirkeby, Agnete, et al.
Publicado: (2013) -
Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease
por: Grealish, Shane, et al.
Publicado: (2014) -
Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease
por: Kirkeby, Agnete, et al.
Publicado: (2017)