Oral colon-specific drug delivery system reduces the nephrotoxicity of rhubarb anthraquinones when they produce purgative efficacy

Rhubarb is commonly used to treat constipation in China and anthraquinones (AQs) are the active components present in rhubarb. However, an increasing number of studies have reported that AQs induce nephrotoxicity. In the present study, rhubarb total free anthraquinones (RTFA) oral colon-specific dru...

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Autores principales: Liu, Pei, Wei, Hongwei, Chang, Jinhua, Miao, Guangxin, Liu, Xigang, Li, Zhongsi, Liu, Liyan, Zhang, Xiangrong, Liu, Cuizhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639398/
https://www.ncbi.nlm.nih.gov/pubmed/29042953
http://dx.doi.org/10.3892/etm.2017.4959

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