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WT1 Is Necessary for the Proliferation and Migration of Cells of Renin Lineage Following Kidney Podocyte Depletion
Wilms' tumor suppressor 1 (WT1) plays an important role in cell proliferation and mesenchymal-epithelial balance in normal development and disease. Here, we show that following podocyte depletion in three experimental models, and in patients with focal segmental glomerulosclerosis (FSGS) and me...
Autores principales: | Kaverina, Natalya V., Eng, Diana G., Largent, Andrea D., Daehn, Ilse, Chang, Anthony, Gross, Kenneth W., Pippin, Jeffrey W., Hohenstein, Peter, Shankland, Stuart J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639431/ https://www.ncbi.nlm.nih.gov/pubmed/28966119 http://dx.doi.org/10.1016/j.stemcr.2017.08.020 |
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