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WT1 Is Necessary for the Proliferation and Migration of Cells of Renin Lineage Following Kidney Podocyte Depletion

Wilms' tumor suppressor 1 (WT1) plays an important role in cell proliferation and mesenchymal-epithelial balance in normal development and disease. Here, we show that following podocyte depletion in three experimental models, and in patients with focal segmental glomerulosclerosis (FSGS) and me...

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Detalles Bibliográficos
Autores principales: Kaverina, Natalya V., Eng, Diana G., Largent, Andrea D., Daehn, Ilse, Chang, Anthony, Gross, Kenneth W., Pippin, Jeffrey W., Hohenstein, Peter, Shankland, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639431/
https://www.ncbi.nlm.nih.gov/pubmed/28966119
http://dx.doi.org/10.1016/j.stemcr.2017.08.020

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