Serendipitous Detection of Extraosseous Metastases on Bone Scintigraphy: Utility of Cross-sectional and Correlative Imaging

Whole body bone scintigraphy is most commonly used imaging modality to detect and assess the extent of osteoblastic osseous metastases in malignant conditions, though visceral metastases need additional imaging. The authors describe a case of 50-year-old postoperative breast cancer female where bone scintigraphy showed soft tissue uptake in thorax and hepatic region in addition to multiple skeletal metastases, indicating the involvement of three different organs by metastatic disease. The present case highlights that extraosseous tracer uptake in addition to abnormal osseous tracer uptake may raise the suspicion of widespread and visceral metastatic disease and warrant further evaluation in the form of cross-sectional and correlative imaging.