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Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria
BACKGROUND: Expression of group A and the A-like subset of group B Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is associated with severe malaria (SM). The diversity of var sequences combined with the challenges of distinct classification of patient pathologies has made studying the...
Autores principales: | Shabani, Estela, Hanisch, Benjamin, Opoka, Robert O., Lavstsen, Thomas, John, Chandy C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639490/ https://www.ncbi.nlm.nih.gov/pubmed/29025399 http://dx.doi.org/10.1186/s12916-017-0945-y |
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