Cargando…
Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism(1). The maternal genome inherited through the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the zygote. How these two epigenetically dis...
Autores principales: | Flyamer, Ilya M., Gassler, Johanna, Imakaev, Maxim, Brandão, Hugo B., Ulianov, Sergey V., Abdennur, Nezar, Razin, Sergey V., Mirny, Leonid A., Tachibana-Konwalski, Kikuë |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639698/ https://www.ncbi.nlm.nih.gov/pubmed/28355183 http://dx.doi.org/10.1038/nature21711 |
Ejemplares similares
-
A mechanism of cohesin‐dependent loop extrusion organizes zygotic genome architecture
por: Gassler, Johanna, et al.
Publicado: (2017) -
Activation of the alpha-globin gene expression correlates with dramatic upregulation of nearby non-globin genes and changes in local and large-scale chromatin spatial structure
por: Ulianov, Sergey V., et al.
Publicado: (2017) -
Chromatin organization by an interplay of loop extrusion and compartmental segregation
por: Nuebler, Johannes, et al.
Publicado: (2018) -
Emerging Evidence of Chromosome Folding by Loop Extrusion
por: Fudenberg, Geoffrey, et al.
Publicado: (2018) -
A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming
por: Ladstätter, Sabrina, et al.
Publicado: (2016)