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Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip

An in vitro model of the human kidney glomerulus — the major site of blood filtration — could facilitate drug discovery and illuminate kidney-disease mechanisms. Microfluidic organ-on-a-chip technology has been used to model the human proximal tubule, yet a kidney-glomerulus-on-a-chip has not been p...

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Detalles Bibliográficos
Autores principales: Musah, Samira, Mammoto, Akiko, Ferrante, Thomas C., Jeanty, Sauveur S. F., Hirano-Kobayashi, Mariko, Mammoto, Tadanori, Roberts, Kristen, Chung, Seyoon, Novak, Richard, Ingram, Miles, Fatanat-Didar, Tohid, Koshy, Sandeep, Weaver, James C., Church, George M., Ingber, Donald E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639718/
https://www.ncbi.nlm.nih.gov/pubmed/29038743
http://dx.doi.org/10.1038/s41551-017-0069