Differential response of the liver to bile acid treatment in a mouse model of Niemann-Pick disease type C

Niemann-Pick disease type C (NPC) disease is a neurodegenerative lysosomal storage disease caused by mutations in the NPC1 or NPC2 genes. Liver disease is also a common feature of NPC that can present as cholestatic jaundice in the neonatal period. Liver enzymes can remain elevated above the normal...

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Detalles Bibliográficos
Autores principales: Nicoli, Elena-Raluca, Huebecker, Mylene, Smith, David, Morris, Lauren, Platt, Frances M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639931/
https://www.ncbi.nlm.nih.gov/pubmed/29062912
http://dx.doi.org/10.12688/wellcomeopenres.12431.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639931/
https://www.ncbi.nlm.nih.gov/pubmed/29062912
http://dx.doi.org/10.12688/wellcomeopenres.12431.2

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