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The “Sandwich Therapy”: A Microsurgical Integrated Approach for Presternal Keloid Treatment

BACKGROUND: Keloid therapy remains a great challenge for plastic surgeons, especially when the defect cannot be closed primarily, necessitating tissue transplantation. Here, we introduce a new treatment modality, called the sandwich therapy, for presternal keloids; the sandwich therapy incorporates...

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Autores principales: Zeng, Ang, Song, Kexin, Zhang, Mingzi, Men, Quancang, Wang, Youbin, Zhu, Lin, Liu, Zhifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640014/
https://www.ncbi.nlm.nih.gov/pubmed/28758907
http://dx.doi.org/10.1097/SAP.0000000000000975
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author Zeng, Ang
Song, Kexin
Zhang, Mingzi
Men, Quancang
Wang, Youbin
Zhu, Lin
Liu, Zhifei
author_facet Zeng, Ang
Song, Kexin
Zhang, Mingzi
Men, Quancang
Wang, Youbin
Zhu, Lin
Liu, Zhifei
author_sort Zeng, Ang
collection PubMed
description BACKGROUND: Keloid therapy remains a great challenge for plastic surgeons, especially when the defect cannot be closed primarily, necessitating tissue transplantation. Here, we introduce a new treatment modality, called the sandwich therapy, for presternal keloids; the sandwich therapy incorporates preradiotherapy, superficial circumflex iliac artery perforator (SCIP) flap transplantation, and postradiotherapy. METHODS: From December 2012 to October 2013, 12 patients received the “sandwich therapy.” For the protocol, all patients went through 5 days of specific events: the precut procedure, preradiotherapy, resection and SCIP flap transplantation, donor site radiotherapy, and final presternal radiotherapy. RESULTS: All the flaps survived completely. No complication was observed during the perioperative period. With a mean follow-up of 12 months, only 1 case was reported with an incisional hypertrophic scar. In all patients, the main discomfort complaints were resolved postoperatively. CONCLUSIONS: A low-tension or without-tension closure could be achieved with SCIP flap transplantation. The perioperative radiotherapy could further lower the risk of keloid recurrence. The sandwich therapy provides a new surgical approach to presternal keloid treatment.
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spelling pubmed-56400142017-10-24 The “Sandwich Therapy”: A Microsurgical Integrated Approach for Presternal Keloid Treatment Zeng, Ang Song, Kexin Zhang, Mingzi Men, Quancang Wang, Youbin Zhu, Lin Liu, Zhifei Ann Plast Surg Microsurgery BACKGROUND: Keloid therapy remains a great challenge for plastic surgeons, especially when the defect cannot be closed primarily, necessitating tissue transplantation. Here, we introduce a new treatment modality, called the sandwich therapy, for presternal keloids; the sandwich therapy incorporates preradiotherapy, superficial circumflex iliac artery perforator (SCIP) flap transplantation, and postradiotherapy. METHODS: From December 2012 to October 2013, 12 patients received the “sandwich therapy.” For the protocol, all patients went through 5 days of specific events: the precut procedure, preradiotherapy, resection and SCIP flap transplantation, donor site radiotherapy, and final presternal radiotherapy. RESULTS: All the flaps survived completely. No complication was observed during the perioperative period. With a mean follow-up of 12 months, only 1 case was reported with an incisional hypertrophic scar. In all patients, the main discomfort complaints were resolved postoperatively. CONCLUSIONS: A low-tension or without-tension closure could be achieved with SCIP flap transplantation. The perioperative radiotherapy could further lower the risk of keloid recurrence. The sandwich therapy provides a new surgical approach to presternal keloid treatment. Lippincott Williams & Wilkins 2017-09 2017-01-10 /pmc/articles/PMC5640014/ /pubmed/28758907 http://dx.doi.org/10.1097/SAP.0000000000000975 Text en Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND (http://creativecommons.org/licenses/by-nc-nd/4.0/) ), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Microsurgery
Zeng, Ang
Song, Kexin
Zhang, Mingzi
Men, Quancang
Wang, Youbin
Zhu, Lin
Liu, Zhifei
The “Sandwich Therapy”: A Microsurgical Integrated Approach for Presternal Keloid Treatment
title The “Sandwich Therapy”: A Microsurgical Integrated Approach for Presternal Keloid Treatment
title_full The “Sandwich Therapy”: A Microsurgical Integrated Approach for Presternal Keloid Treatment
title_fullStr The “Sandwich Therapy”: A Microsurgical Integrated Approach for Presternal Keloid Treatment
title_full_unstemmed The “Sandwich Therapy”: A Microsurgical Integrated Approach for Presternal Keloid Treatment
title_short The “Sandwich Therapy”: A Microsurgical Integrated Approach for Presternal Keloid Treatment
title_sort “sandwich therapy”: a microsurgical integrated approach for presternal keloid treatment
topic Microsurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640014/
https://www.ncbi.nlm.nih.gov/pubmed/28758907
http://dx.doi.org/10.1097/SAP.0000000000000975
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