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Cost-effectiveness of stroke care in Aboriginal and non-Aboriginal patients: an observational cohort study in the Northern Territory of Australia

OBJECTIVE: To assess cost-effectiveness of stroke care for Aboriginal compared with non-Aboriginal patients in the Northern Territory (NT), Australia. DESIGN: Cost-effectiveness analysis using data from a cohort-based follow-up study of stroke incidents. SETTING: Public hospitals in the NT from 1992...

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Autores principales: Zhao, Yuejen, Guthridge, Steven, Falhammar, Henrik, Flavell, Howard, Cadilhac, Dominique A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Open 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640075/
https://www.ncbi.nlm.nih.gov/pubmed/28982808
http://dx.doi.org/10.1136/bmjopen-2016-015033
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author Zhao, Yuejen
Guthridge, Steven
Falhammar, Henrik
Flavell, Howard
Cadilhac, Dominique A
author_facet Zhao, Yuejen
Guthridge, Steven
Falhammar, Henrik
Flavell, Howard
Cadilhac, Dominique A
author_sort Zhao, Yuejen
collection PubMed
description OBJECTIVE: To assess cost-effectiveness of stroke care for Aboriginal compared with non-Aboriginal patients in the Northern Territory (NT), Australia. DESIGN: Cost-effectiveness analysis using data from a cohort-based follow-up study of stroke incidents. SETTING: Public hospitals in the NT from 1992 to 2013. PARTICIPANTS: Individual patient data were extracted and linked from the hospital inpatient and primary care information systems. OUTCOME MEASURES: Incremental cost-effectiveness ratios were calculated and assessed graphically. Survival time was used to measure effectiveness of stroke care, in comparison with the net costs per life-year gained, from a healthcare perspective, by applying multivariable models to account for time-dependent confounding. RESULTS: 2158 patients with incident stroke were included (1171 males, 1178 aged <65 years and 966 from remote areas). 992 patients were of Aboriginal origin (46.0%, disproportionately higher than the population proportion of 27%). Of all cases, 42.6% were ischaemic and 29.8% haemorrhagic stroke. Average age of stroke onset was 51 years in Aboriginal, compared with 65 years in non-Aboriginal patients (p<0.001). Aboriginal patients had 71.4% more hospital bed-days, and 7.4% fewer procedures than non-Aboriginal patients. Observed health costs averaged $A50 400 per Aboriginal compared with $A33 700 per non-Aboriginal patient (p<0.001). The differential costs and effects for each population were distributed evenly across the incremental cost-effectiveness plane threshold line, indicating no difference in cost-effectiveness between populations. After further adjustment for confounding and censoring, cost-effectiveness appeared greater for Aboriginal than non-Aboriginal patients, but this was not statistically significant (p=0.25). CONCLUSIONS: Stroke care for the NT Aboriginal population is at least as cost-effective as the non-Aboriginal population. Stroke care presents worthwhile and equitable survival benefits for Aboriginal patients in remote communities, notwithstanding their higher level burden of disease. These findings are relevant for healthcare planning and policy development regarding equal access to stroke care for Aboriginal patients.
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spelling pubmed-56400752017-10-19 Cost-effectiveness of stroke care in Aboriginal and non-Aboriginal patients: an observational cohort study in the Northern Territory of Australia Zhao, Yuejen Guthridge, Steven Falhammar, Henrik Flavell, Howard Cadilhac, Dominique A BMJ Open Health Economics OBJECTIVE: To assess cost-effectiveness of stroke care for Aboriginal compared with non-Aboriginal patients in the Northern Territory (NT), Australia. DESIGN: Cost-effectiveness analysis using data from a cohort-based follow-up study of stroke incidents. SETTING: Public hospitals in the NT from 1992 to 2013. PARTICIPANTS: Individual patient data were extracted and linked from the hospital inpatient and primary care information systems. OUTCOME MEASURES: Incremental cost-effectiveness ratios were calculated and assessed graphically. Survival time was used to measure effectiveness of stroke care, in comparison with the net costs per life-year gained, from a healthcare perspective, by applying multivariable models to account for time-dependent confounding. RESULTS: 2158 patients with incident stroke were included (1171 males, 1178 aged <65 years and 966 from remote areas). 992 patients were of Aboriginal origin (46.0%, disproportionately higher than the population proportion of 27%). Of all cases, 42.6% were ischaemic and 29.8% haemorrhagic stroke. Average age of stroke onset was 51 years in Aboriginal, compared with 65 years in non-Aboriginal patients (p<0.001). Aboriginal patients had 71.4% more hospital bed-days, and 7.4% fewer procedures than non-Aboriginal patients. Observed health costs averaged $A50 400 per Aboriginal compared with $A33 700 per non-Aboriginal patient (p<0.001). The differential costs and effects for each population were distributed evenly across the incremental cost-effectiveness plane threshold line, indicating no difference in cost-effectiveness between populations. After further adjustment for confounding and censoring, cost-effectiveness appeared greater for Aboriginal than non-Aboriginal patients, but this was not statistically significant (p=0.25). CONCLUSIONS: Stroke care for the NT Aboriginal population is at least as cost-effective as the non-Aboriginal population. Stroke care presents worthwhile and equitable survival benefits for Aboriginal patients in remote communities, notwithstanding their higher level burden of disease. These findings are relevant for healthcare planning and policy development regarding equal access to stroke care for Aboriginal patients. BMJ Open 2017-10-05 /pmc/articles/PMC5640075/ /pubmed/28982808 http://dx.doi.org/10.1136/bmjopen-2016-015033 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Health Economics
Zhao, Yuejen
Guthridge, Steven
Falhammar, Henrik
Flavell, Howard
Cadilhac, Dominique A
Cost-effectiveness of stroke care in Aboriginal and non-Aboriginal patients: an observational cohort study in the Northern Territory of Australia
title Cost-effectiveness of stroke care in Aboriginal and non-Aboriginal patients: an observational cohort study in the Northern Territory of Australia
title_full Cost-effectiveness of stroke care in Aboriginal and non-Aboriginal patients: an observational cohort study in the Northern Territory of Australia
title_fullStr Cost-effectiveness of stroke care in Aboriginal and non-Aboriginal patients: an observational cohort study in the Northern Territory of Australia
title_full_unstemmed Cost-effectiveness of stroke care in Aboriginal and non-Aboriginal patients: an observational cohort study in the Northern Territory of Australia
title_short Cost-effectiveness of stroke care in Aboriginal and non-Aboriginal patients: an observational cohort study in the Northern Territory of Australia
title_sort cost-effectiveness of stroke care in aboriginal and non-aboriginal patients: an observational cohort study in the northern territory of australia
topic Health Economics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640075/
https://www.ncbi.nlm.nih.gov/pubmed/28982808
http://dx.doi.org/10.1136/bmjopen-2016-015033
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