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Removing dysfunctional mitochondria from axons independent of mitophagy under pathophysiological conditions
Chronic mitochondrial dysfunction has been implicated in major neurodegenerative diseases. Long-term cumulative pathological stress leads to axonal accumulation of damaged mitochondria. Therefore, the early removal of defective mitochondria from axons constitutes a critical step of mitochondrial qua...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640196/ https://www.ncbi.nlm.nih.gov/pubmed/28812939 http://dx.doi.org/10.1080/15548627.2017.1356552 |