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Removing dysfunctional mitochondria from axons independent of mitophagy under pathophysiological conditions

Chronic mitochondrial dysfunction has been implicated in major neurodegenerative diseases. Long-term cumulative pathological stress leads to axonal accumulation of damaged mitochondria. Therefore, the early removal of defective mitochondria from axons constitutes a critical step of mitochondrial qua...

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Detalles Bibliográficos
Autores principales: Lin, Mei-Yao, Cheng, Xiu-Tang, Xie, Yuxiang, Cai, Qian, Sheng, Zu-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640196/
https://www.ncbi.nlm.nih.gov/pubmed/28812939
http://dx.doi.org/10.1080/15548627.2017.1356552