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ER stress and subsequent activated calpain play a pivotal role in skeletal muscle wasting after severe burn injury
Severe burns are typically followed by hypermetabolism characterized by significant muscle wasting, which causes considerable morbidity and mortality. The aim of the present study was to explore the underlying mechanisms of skeletal muscle damage/wasting post-burn. Rats were randomized to the sham,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640216/ https://www.ncbi.nlm.nih.gov/pubmed/29028830 http://dx.doi.org/10.1371/journal.pone.0186128 |