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Comparison of acute kidney injury between open and laparoscopic liver resection: Propensity score analysis

The inflammatory response has been shown to be a major contributor to acute kidney injury. Considering that laparoscopic surgery is beneficial in reducing the inflammatory response, we compared the incidence of postoperative acute kidney injury between laparoscopic liver resection and open liver res...

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Autores principales: Moon, Young-Jin, Jun, In-Gu, Kim, Ki-Hun, Kim, Seon-Ok, Song, Jun-Gol, Hwang, Gyu-Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640237/
https://www.ncbi.nlm.nih.gov/pubmed/29028816
http://dx.doi.org/10.1371/journal.pone.0186336
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author Moon, Young-Jin
Jun, In-Gu
Kim, Ki-Hun
Kim, Seon-Ok
Song, Jun-Gol
Hwang, Gyu-Sam
author_facet Moon, Young-Jin
Jun, In-Gu
Kim, Ki-Hun
Kim, Seon-Ok
Song, Jun-Gol
Hwang, Gyu-Sam
author_sort Moon, Young-Jin
collection PubMed
description The inflammatory response has been shown to be a major contributor to acute kidney injury. Considering that laparoscopic surgery is beneficial in reducing the inflammatory response, we compared the incidence of postoperative acute kidney injury between laparoscopic liver resection and open liver resection. Among 1173 patients who underwent liver resection surgery, 222 of 926 patients who underwent open liver resection were matched with 222 of 247 patients who underwent laparoscopic liver resection, by using propensity score analysis. The incidence of postoperative acute kidney injury assessed according to the creatinine criteria of the Kidney Disease: Improving Global Outcomes definition was compared between those 1:1 matched groups. A total 77 (6.6%) cases of postoperative acute kidney injury occurred. Before matching, the incidence of acute kidney injury after laparoscopic liver resection was significantly lower than that after open liver resection [1.6% (4/247) vs. 7.9% (73/926), P < 0.001]. After 1:1 matching, the incidence of postoperative acute kidney injury was still significantly lower after laparoscopic liver resection than after open liver resection [1.8% (4/222) vs. 6.3% (14/222), P = 0.008; odds ratio 0.273, 95% confidence interval 0.088–0.842, P = 0.024]. The postoperative inflammatory marker was also lower in laparoscopic liver resection than in open liver resection in matched set data (white blood cell count 12.7 ± 4.0 × 10(3)/μL vs. 14.9 ± 3.9 × 10(3)/μL, P < 0.001). Our findings suggest that the laparoscopic technique, by decreasing the inflammatory response, may reduce the occurrence of postoperative acute kidney injury during liver resection surgery.
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spelling pubmed-56402372017-10-30 Comparison of acute kidney injury between open and laparoscopic liver resection: Propensity score analysis Moon, Young-Jin Jun, In-Gu Kim, Ki-Hun Kim, Seon-Ok Song, Jun-Gol Hwang, Gyu-Sam PLoS One Research Article The inflammatory response has been shown to be a major contributor to acute kidney injury. Considering that laparoscopic surgery is beneficial in reducing the inflammatory response, we compared the incidence of postoperative acute kidney injury between laparoscopic liver resection and open liver resection. Among 1173 patients who underwent liver resection surgery, 222 of 926 patients who underwent open liver resection were matched with 222 of 247 patients who underwent laparoscopic liver resection, by using propensity score analysis. The incidence of postoperative acute kidney injury assessed according to the creatinine criteria of the Kidney Disease: Improving Global Outcomes definition was compared between those 1:1 matched groups. A total 77 (6.6%) cases of postoperative acute kidney injury occurred. Before matching, the incidence of acute kidney injury after laparoscopic liver resection was significantly lower than that after open liver resection [1.6% (4/247) vs. 7.9% (73/926), P < 0.001]. After 1:1 matching, the incidence of postoperative acute kidney injury was still significantly lower after laparoscopic liver resection than after open liver resection [1.8% (4/222) vs. 6.3% (14/222), P = 0.008; odds ratio 0.273, 95% confidence interval 0.088–0.842, P = 0.024]. The postoperative inflammatory marker was also lower in laparoscopic liver resection than in open liver resection in matched set data (white blood cell count 12.7 ± 4.0 × 10(3)/μL vs. 14.9 ± 3.9 × 10(3)/μL, P < 0.001). Our findings suggest that the laparoscopic technique, by decreasing the inflammatory response, may reduce the occurrence of postoperative acute kidney injury during liver resection surgery. Public Library of Science 2017-10-13 /pmc/articles/PMC5640237/ /pubmed/29028816 http://dx.doi.org/10.1371/journal.pone.0186336 Text en © 2017 Moon et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Moon, Young-Jin
Jun, In-Gu
Kim, Ki-Hun
Kim, Seon-Ok
Song, Jun-Gol
Hwang, Gyu-Sam
Comparison of acute kidney injury between open and laparoscopic liver resection: Propensity score analysis
title Comparison of acute kidney injury between open and laparoscopic liver resection: Propensity score analysis
title_full Comparison of acute kidney injury between open and laparoscopic liver resection: Propensity score analysis
title_fullStr Comparison of acute kidney injury between open and laparoscopic liver resection: Propensity score analysis
title_full_unstemmed Comparison of acute kidney injury between open and laparoscopic liver resection: Propensity score analysis
title_short Comparison of acute kidney injury between open and laparoscopic liver resection: Propensity score analysis
title_sort comparison of acute kidney injury between open and laparoscopic liver resection: propensity score analysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640237/
https://www.ncbi.nlm.nih.gov/pubmed/29028816
http://dx.doi.org/10.1371/journal.pone.0186336
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