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EGFR T790M: revealing the secrets of a gatekeeper

Non-small-cell lung cancers that harbor activating mutations in the EGFR gene represent an important molecularly defined subset of lung cancer. Despite dramatic initial responses with first- and second-generation EGFR-directed tyrosine-kinase inhibitors (TKIs) against these cancers, the development...

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Detalles Bibliográficos
Autores principales:	Ko, Brian, Paucar, Daniel, Halmos, Balazs
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640399/ https://www.ncbi.nlm.nih.gov/pubmed/29070957 http://dx.doi.org/10.2147/LCTT.S117944

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