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A combined 3D-SIM/SMLM approach allows centriole proteins to be localized with a precision of ∼4–5 nm

Centrioles are small barrel-shaped structures that form centrosomes and cilia [1]. Centrioles assemble around a central cartwheel comprising the Sas-6 and Ana2/STIL proteins. The amino termini of nine Sas-6 dimers form a central hub of ∼12 nm radius from which nine dimer spokes radiate, placing the...

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Detalles Bibliográficos
Autores principales: Gartenmann, Lisa, Wainman, Alan, Qurashi, Maryam, Kaufmann, Rainer, Schubert, Sebastian, Raff, Jordan W., Dobbie, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640508/
https://www.ncbi.nlm.nih.gov/pubmed/29017036
http://dx.doi.org/10.1016/j.cub.2017.08.009

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