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BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling

The spindle assembly checkpoint (SAC) prevents premature sister chromatid separation during mitosis. Phosphorylation of unattached kinetochores by the Mps1 kinase promotes recruitment of SAC machinery that catalyzes assembly of the SAC effector mitotic checkpoint complex (MCC). The SAC protein Bub3...

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Detalles Bibliográficos
Autores principales:	Overlack, Katharina, Bange, Tanja, Weissmann, Florian, Faesen, Alex C., Maffini, Stefano, Primorac, Ivana, Müller, Franziska, Peters, Jan-Michael, Musacchio, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640511/ https://www.ncbi.nlm.nih.gov/pubmed/28943088 http://dx.doi.org/10.1016/j.cub.2017.08.033

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