Mesenchymal stem cells from tumor microenvironment favour breast cancer stem cell proliferation, cancerogenic and metastatic potential, via ionotropic purinergic signalling

Interaction between tumor cells and the microenvironment is key in initiation, progression, and invasiveness of cancer. In particular, mesenchymal stem cells (MSCs) are recruited to the sites of developing tumors, thus promoting metastasis formation. Although it is well known that MSCs migrate and i...

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Detalles Bibliográficos
Autores principales: Maffey, A., Storini, C., Diceglie, C., Martelli, C., Sironi, L., Calzarossa, C., Tonna, N., Lovchik, R., Delamarche, E., Ottobrini, L., Bianco, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640614/
https://www.ncbi.nlm.nih.gov/pubmed/29030596
http://dx.doi.org/10.1038/s41598-017-13460-7

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