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Impaired branched-chain amino acid metabolism may underlie the nonalcoholic fatty liver disease-like pathology of neonatal testosterone-treated female rats

Polycystic ovary syndrome (PCOS) is frequently associated with non-alcoholic fatty liver disease (NAFLD), but the mechanisms involved in the development of NAFLD in PCOS are not well known. We investigated histological changes and metabolomic profile in the liver of rat models of PCOS phenotype indu...

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Detalles Bibliográficos
Autores principales:	Anzai, Álvaro, Marcondes, Rodrigo R., Gonçalves, Thiago H., Carvalho, Kátia C., Simões, Manuel J., Garcia, Natália, Soares, José M., Padmanabhan, Vasantha, Baracat, Edmund C., da Silva, Ismael D. C. G., Maciel, Gustavo A. R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640623/ https://www.ncbi.nlm.nih.gov/pubmed/29030588 http://dx.doi.org/10.1038/s41598-017-13451-8

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