Lipopolysaccharide enters the rat brain by a lipoprotein-mediated transport mechanism in physiological conditions

Physiologically, lipopolysaccharide (LPS) is present in the bloodstream and can be bound to several proteins for its transport (i.e.) LPS binding protein (LBP) and plasma lipoproteins). LPS receptors CD14 and TLR-4 are constitutively expressed in the Central Nervous System (CNS). To our knowledge, L...

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Detalles Bibliográficos
Autores principales: Vargas-Caraveo, Alejandra, Sayd, Aline, Maus, Sandra R., Caso, Javier R., Madrigal, José L. M., García-Bueno, Borja, Leza, Juan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640642/
https://www.ncbi.nlm.nih.gov/pubmed/29030613
http://dx.doi.org/10.1038/s41598-017-13302-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640642/
https://www.ncbi.nlm.nih.gov/pubmed/29030613
http://dx.doi.org/10.1038/s41598-017-13302-6

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