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Interfering with the high-affinity interaction between wheat amylase trypsin inhibitor CM3 and toll-like receptor 4: in silico and biosensor-based studies

Wheat amylase/trypsin bi-functional inhibitors (ATIs) are protein stimulators of innate immune response, with a recently established role in promoting both gastrointestinal and extra-gastrointestinal inflammatory syndromes. These proteins have been reported to trigger downstream intestinal inflammat...

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Detalles Bibliográficos
Autores principales:	Cuccioloni, Massimiliano, Mozzicafreddo, Matteo, Bonfili, Laura, Cecarini, Valentina, Giangrossi, Mara, Falconi, Maurizio, Saitoh, Shin-Ichiroh, Eleuteri, Anna Maria, Angeletti, Mauro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640651/ https://www.ncbi.nlm.nih.gov/pubmed/29030601 http://dx.doi.org/10.1038/s41598-017-13709-1

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