DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells

Determining cell identity and maturation status of differentiated pluripotent stem cells (PSCs) requires knowledge of the transcriptional and epigenetic trajectory of organs during development. Here, we generate a transcriptional and DNA methylation atlas covering 21 organs during human fetal develo...

Descripción completa

Detalles Bibliográficos
Autores principales: Roost, Matthias S., Slieker, Roderick C., Bialecka, Monika, van Iperen, Liesbeth, Gomes Fernandes, Maria M., He, Nannan, Suchiman, H. Eka D., Szuhai, Karoly, Carlotti, Françoise, de Koning, Eelco J. P., Mummery, Christine L., Heijmans, Bastiaan T., Chuva de Sousa Lopes, Susana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640655/
https://www.ncbi.nlm.nih.gov/pubmed/29030611
http://dx.doi.org/10.1038/s41467-017-01077-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640655/
https://www.ncbi.nlm.nih.gov/pubmed/29030611
http://dx.doi.org/10.1038/s41467-017-01077-3

Ejemplares similares