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Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface
Lubricin, a heavily O-glycosylated protein, is essential for boundary lubrication of articular cartilage. Strong surface adherence of lubricin is required given the extreme force it must withstand. Disulfide bound complexes of lubricin and cartilage oligomeric matrix protein (COMP) have recently bee...
Autores principales: | Flowers, Sarah A., Zieba, Agata, Örnros, Jessica, Jin, Chunsheng, Rolfson, Ola, Björkman, Lena I., Eisler, Thomas, Kalamajski, Sebastian, Kamali-Moghaddam, Masood, Karlsson, Niclas G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640667/ https://www.ncbi.nlm.nih.gov/pubmed/29030641 http://dx.doi.org/10.1038/s41598-017-13558-y |
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