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Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2

PGLa and magainin 2 (MAG2) are amphiphilic α-helical membranolytic peptides from frog skin with known synergistic antimicrobial activity. By systematically mutating residues in the two peptides it was possible to identify the ones crucial for the synergy, as monitored by biological assays, fluoresce...

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Detalles Bibliográficos
Autores principales:	Zerweck, Jonathan, Strandberg, Erik, Kukharenko, Olga, Reichert, Johannes, Bürck, Jochen, Wadhwani, Parvesh, Ulrich, Anne S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640672/ https://www.ncbi.nlm.nih.gov/pubmed/29030606 http://dx.doi.org/10.1038/s41598-017-12599-7

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