First molecular characterization of canine parvovirus strains in Sardinia, Italy

Canine parvovirus type 2 (CPV-2) is responsible of acute hemorrhagic gastroenteritis in young dogs. CPV-2 emerged in 1978 in the USA, but new antigenic types, CPV-2a, 2b and 2c, have completely replaced the original type. In this study, we analyzed 81 animals collected in Sardinia, Italy. The VP2 se...

Descripción completa

Detalles Bibliográficos
Autores principales: Dei Giudici, S., Cubeddu, T., Giagu, A., Sanna, G., Rocca, S., Oggiano, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2017
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640725/
https://www.ncbi.nlm.nih.gov/pubmed/28707272
http://dx.doi.org/10.1007/s00705-017-3457-3
_version_ 1783271087036956672
author Dei Giudici, S.
Cubeddu, T.
Giagu, A.
Sanna, G.
Rocca, S.
Oggiano, A.
author_facet Dei Giudici, S.
Cubeddu, T.
Giagu, A.
Sanna, G.
Rocca, S.
Oggiano, A.
author_sort Dei Giudici, S.
collection PubMed
description Canine parvovirus type 2 (CPV-2) is responsible of acute hemorrhagic gastroenteritis in young dogs. CPV-2 emerged in 1978 in the USA, but new antigenic types, CPV-2a, 2b and 2c, have completely replaced the original type. In this study, we analyzed 81 animals collected in Sardinia, Italy. The VP2 sequence analysis of 27 positive samples showed that all antigenic CPV-2 types are circulating. CPV-2b seems to be the most widespread variant, followed by CPV-2a. Furthermore, 12 CPV-2b strains displayed further amino acid substitutions and formed a separate cluster in a phylogenetic tree, indicating regional genetic variation.
format Online
Article
Text
id pubmed-5640725
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Springer Vienna
record_format MEDLINE/PubMed
spelling pubmed-56407252017-10-26 First molecular characterization of canine parvovirus strains in Sardinia, Italy Dei Giudici, S. Cubeddu, T. Giagu, A. Sanna, G. Rocca, S. Oggiano, A. Arch Virol Brief Report Canine parvovirus type 2 (CPV-2) is responsible of acute hemorrhagic gastroenteritis in young dogs. CPV-2 emerged in 1978 in the USA, but new antigenic types, CPV-2a, 2b and 2c, have completely replaced the original type. In this study, we analyzed 81 animals collected in Sardinia, Italy. The VP2 sequence analysis of 27 positive samples showed that all antigenic CPV-2 types are circulating. CPV-2b seems to be the most widespread variant, followed by CPV-2a. Furthermore, 12 CPV-2b strains displayed further amino acid substitutions and formed a separate cluster in a phylogenetic tree, indicating regional genetic variation. Springer Vienna 2017-07-14 2017 /pmc/articles/PMC5640725/ /pubmed/28707272 http://dx.doi.org/10.1007/s00705-017-3457-3 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Dei Giudici, S.
Cubeddu, T.
Giagu, A.
Sanna, G.
Rocca, S.
Oggiano, A.
First molecular characterization of canine parvovirus strains in Sardinia, Italy
title First molecular characterization of canine parvovirus strains in Sardinia, Italy
title_full First molecular characterization of canine parvovirus strains in Sardinia, Italy
title_fullStr First molecular characterization of canine parvovirus strains in Sardinia, Italy
title_full_unstemmed First molecular characterization of canine parvovirus strains in Sardinia, Italy
title_short First molecular characterization of canine parvovirus strains in Sardinia, Italy
title_sort first molecular characterization of canine parvovirus strains in sardinia, italy
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640725/
https://www.ncbi.nlm.nih.gov/pubmed/28707272
http://dx.doi.org/10.1007/s00705-017-3457-3
work_keys_str_mv AT deigiudicis firstmolecularcharacterizationofcanineparvovirusstrainsinsardiniaitaly
AT cubeddut firstmolecularcharacterizationofcanineparvovirusstrainsinsardiniaitaly
AT giagua firstmolecularcharacterizationofcanineparvovirusstrainsinsardiniaitaly
AT sannag firstmolecularcharacterizationofcanineparvovirusstrainsinsardiniaitaly
AT roccas firstmolecularcharacterizationofcanineparvovirusstrainsinsardiniaitaly
AT oggianoa firstmolecularcharacterizationofcanineparvovirusstrainsinsardiniaitaly

Ejemplares similares