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pH-Dependant Antifungal Activity of Valproic Acid against the Human Fungal Pathogen Candida albicans

Current antifungal drugs suffer from limitations including toxicity, the emergence of resistance and decreased efficacy at low pH that are typical of human vaginal surfaces. Here, we have shown that the antipsychotic drug valproic acid (VPA) exhibited a strong antifungal activity against both sensit...

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Detalles Bibliográficos
Autores principales:	Chaillot, Julien, Tebbji, Faiza, García, Carlos, Wurtele, Hugo, Pelletier, René, Sellam, Adnane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640775/ https://www.ncbi.nlm.nih.gov/pubmed/29062309 http://dx.doi.org/10.3389/fmicb.2017.01956

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