Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer

Acremonium chrysogenum is an important filamentous fungus which produces cephalosporin C in industry. This review summarized the study on genetic engineering of Acremonium chrysogenum, including biosynthesis and regulation for fermentation of cephalosporin C, molecular techniques, molecular breeding...

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Detalles Bibliográficos
Autores principales: Hu, Youjia, Zhu, Baoquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640796/
https://www.ncbi.nlm.nih.gov/pubmed/29062938
http://dx.doi.org/10.1016/j.synbio.2016.09.002
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author Hu, Youjia
Zhu, Baoquan
author_facet Hu, Youjia
Zhu, Baoquan
author_sort Hu, Youjia
collection PubMed
description Acremonium chrysogenum is an important filamentous fungus which produces cephalosporin C in industry. This review summarized the study on genetic engineering of Acremonium chrysogenum, including biosynthesis and regulation for fermentation of cephalosporin C, molecular techniques, molecular breeding and transcriptomics of Acremonium chrysogenum. We believe with all the techniques available and full genomic sequence, the industrial strain of Acremonium chrysogenum can be genetically modified to better serve the pharmaceutical industry.
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spelling pubmed-56407962017-10-23 Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer Hu, Youjia Zhu, Baoquan Synth Syst Biotechnol Article Acremonium chrysogenum is an important filamentous fungus which produces cephalosporin C in industry. This review summarized the study on genetic engineering of Acremonium chrysogenum, including biosynthesis and regulation for fermentation of cephalosporin C, molecular techniques, molecular breeding and transcriptomics of Acremonium chrysogenum. We believe with all the techniques available and full genomic sequence, the industrial strain of Acremonium chrysogenum can be genetically modified to better serve the pharmaceutical industry. KeAi Publishing 2016-09-25 /pmc/articles/PMC5640796/ /pubmed/29062938 http://dx.doi.org/10.1016/j.synbio.2016.09.002 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Hu, Youjia
Zhu, Baoquan
Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer
title Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer
title_full Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer
title_fullStr Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer
title_full_unstemmed Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer
title_short Study on genetic engineering of Acremonium chrysogenum, the cephalosporin C producer
title_sort study on genetic engineering of acremonium chrysogenum, the cephalosporin c producer
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640796/
https://www.ncbi.nlm.nih.gov/pubmed/29062938
http://dx.doi.org/10.1016/j.synbio.2016.09.002
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