An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABA(A) Receptors

Inhibitory synaptic transmission requires the targeting and stabilization of GABA(A) receptors (GABA(A)Rs) at synapses. The mechanisms responsible remain poorly understood, and roles for transmembrane accessory proteins have not been established. Using molecular, imaging, and electrophysiological ap...

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Detalles Bibliográficos
Autores principales: Davenport, Elizabeth C., Pendolino, Valentina, Kontou, Georgina, McGee, Thomas P., Sheehan, David F., López-Doménech, Guillermo, Farrant, Mark, Kittler, Josef T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640807/
https://www.ncbi.nlm.nih.gov/pubmed/28978485
http://dx.doi.org/10.1016/j.celrep.2017.09.025

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