Cargando…

A Single-Amino-Acid Substitution at Position 225 in Hemagglutinin Alters the Transmissibility of Eurasian Avian-Like H1N1 Swine Influenza Virus in Guinea Pigs

Efficient transmission from human to human is the prerequisite for an influenza virus to cause a pandemic; however, the molecular determinants of influenza virus transmission are still largely unknown. In this study, we explored the molecular basis for transmission of Eurasian avian-like H1N1 (EAH1N...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zeng, Yang, Huanliang, Chen, Yan, Tao, Shiyu, Liu, Liling, Kong, Huihui, Ma, Shujie, Meng, Fei, Suzuki, Yasuo, Qiao, Chuanling, Chen, Hualan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640871/ https://www.ncbi.nlm.nih.gov/pubmed/28814518 http://dx.doi.org/10.1128/JVI.00800-17

Ejemplares similares

Glycine at Position 622 in PB1 Contributes to the Virulence of H5N1 Avian Influenza Virus in Mice
por: Feng, Xiaoxiao, et al.
Publicado: (2016)

Glycosylation of the Hemagglutinin Protein of H5N1 Influenza Virus Increases Its Virulence in Mice by Exacerbating the Host Immune Response
por: Zhao, Dongming, et al.
Publicado: (2017)

A Single Amino Acid at Position 431 of the PB2 Protein Determines the Virulence of H1N1 Swine Influenza Viruses in Mice
por: Xu, Chengzhi, et al.
Publicado: (2020)

Immune Escape Adaptive Mutations in Hemagglutinin Are Responsible for the Antigenic Drift of Eurasian Avian-Like H1N1 Swine Influenza Viruses
por: Xu, Chengzhi, et al.
Publicado: (2022)

Amino Acid Mutations A286V and T437M in the Nucleoprotein Attenuate H7N9 Viruses in Mice
por: Ma, Shujie, et al.
Publicado: (2020)

Assessing the Protective Potential of H1N1 Influenza Virus Hemagglutinin Head and Stalk Antibodies in Humans
por: Christensen, Shannon R., et al.
Publicado: (2019)

Genetic Compatibility of Reassortants between Avian H5N1 and H9N2 Influenza Viruses with Higher Pathogenicity in Mammals
por: Arai, Yasuha, et al.
Publicado: (2019)

Hemagglutinin and Neuraminidase Antibodies Are Induced in an Age- and Subtype-Dependent Manner after Influenza Virus Infection
por: Wong, Sook-San, et al.
Publicado: (2020)

Pathobiology of an NS1-Truncated H3N2 Swine Influenza Virus Strain in Pigs
por: Vandoorn, Elien, et al.
Publicado: (2022)

Evaluation of the Interactions between Mumps Virus and Guinea Pig
por: Lang Balija, Maja, et al.
Publicado: (2023)

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases
por: Kühn, Nora, et al.
Publicado: (2016)

Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics
por: Peacock, Thomas P., et al.
Publicado: (2017)

Differential Effect of Deleting Members of African Swine Fever Virus Multigene Families 360 and 505 from the Genotype II Georgia 2007/1 Isolate on Virus Replication, Virulence, and Induction of Protection
por: Rathakrishnan, Anusyah, et al.
Publicado: (2022)

The African swine fever virus I10L protein inhibits the NF-κB signaling pathway by targeting IKKβ
por: Chen, Xing, et al.
Publicado: (2023)

Contribution of Segment 3 to the Acquisition of Virulence in Contemporary H9N2 Avian Influenza Viruses
por: Clements, Anabel L., et al.
Publicado: (2020)

The Furin-S2′ Site in Avian Coronavirus Plays a Key Role in Central Nervous System Damage Progression
por: Cheng, Jinlong, et al.
Publicado: (2021)

A Temperature-Sensitive Recombinant of Avian Coronavirus Infectious Bronchitis Virus Provides Complete Protection against Homologous Challenge
por: Keep, Sarah, et al.
Publicado: (2022)

The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical Swine Fever Virus Is Responsible for Viral Attenuation and Protection against Lethal Challenge
por: Li, Yongfeng, et al.
Publicado: (2022)

African swine fever virus B175L inhibits the type I interferon pathway by targeting STING and 2′3′-cGAMP
por: Ranathunga, Lakmal, et al.
Publicado: (2023)

Combinational Deletions of MGF110-9L and MGF505-7R Genes from the African Swine Fever Virus Inhibit TBK1 Degradation by an Autophagy Activator PIK3C2B To Promote Type I Interferon Production
por: Zhu, Guoqiang, et al.
Publicado: (2023)

Identification of Amino Acids within Nonstructural Proteins 10 and 14 of the Avian Coronavirus Infectious Bronchitis Virus That Result in Attenuation In Vivo and In Ovo
por: Keep, Sarah, et al.
Publicado: (2022)

Long-Term Protective Effect of Serial Infections with H5N8 Highly Pathogenic Avian Influenza Virus in Wild Ducks
por: Caliendo, Valentina, et al.
Publicado: (2022)

African Swine Fever Virus EP364R and C129R Target Cyclic GMP-AMP To Inhibit the cGAS-STING Signaling Pathway
por: Dodantenna, Niranjan, et al.
Publicado: (2022)

Combinational Deletions of MGF360-9L and MGF505-7R Attenuated Highly Virulent African Swine Fever Virus and Conferred Protection against Homologous Challenge
por: Ding, Mingyang, et al.
Publicado: (2022)

Deletion of the African Swine Fever Virus Gene DP148R Does Not Reduce Virus Replication in Culture but Reduces Virus Virulence in Pigs and Induces High Levels of Protection against Challenge
por: Reis, Ana L., et al.
Publicado: (2017)

Role of African Swine Fever Virus Proteins EP153R and EP402R in Reducing Viral Persistence in Blood and Virulence in Pigs Infected with BeninΔDP148R
por: Petrovan, Vlad, et al.
Publicado: (2022)

The Omicron Variant BA.1.1 Presents a Lower Pathogenicity than B.1 D614G and Delta Variants in a Feline Model of SARS-CoV-2 Infection
por: Martins, Mathias, et al.
Publicado: (2022)

A Eurasian avian-like H1N1 swine influenza reassortant virus became pathogenic and highly transmissible due to mutations in its PA gene
por: Meng, Fei, et al.
Publicado: (2022)

Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-1
por: Zhang, Yu, et al.
Publicado: (2020)

SUMO Ligase Protein Inhibitor of Activated STAT1 (PIAS1) Is a Constituent Promyelocytic Leukemia Nuclear Body Protein That Contributes to the Intrinsic Antiviral Immune Response to Herpes Simplex Virus 1
por: Brown, James R., et al.
Publicado: (2016)

Establishment of a Cynomolgus Macaque Model of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Infection by Direct Inoculation of Adult T-Cell Leukemia Patient-Derived Cell Lines for HTLV-1 Infection
por: Urano, Emiko, et al.
Publicado: (2022)

CD32(+) and PD-1(+) Lymph Node CD4 T Cells Support Persistent HIV-1 Transcription in Treated Aviremic Individuals
por: Noto, Alessandra, et al.
Publicado: (2018)

Inefficient HIV-1 trans Infection of CD4(+) T Cells by Macrophages from HIV-1 Nonprogressors Is Associated with Altered Membrane Cholesterol and DC-SIGN
por: DeLucia, Diana C., et al.
Publicado: (2018)

Control of HIV-1 Replication by CD8(+) T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection
por: Nguyen, Hung The, et al.
Publicado: (2022)

Leukocyte Immunoglobulin-Like Receptor 1-Expressing Human Natural Killer Cell Subsets Differentially Recognize Isolates of Human Cytomegalovirus through the Viral Major Histocompatibility Complex Class I Homolog UL18
por: Chen, Kevin C., et al.
Publicado: (2016)

Spontaneous and Vaccine-Induced Clearance of Mus Musculus Papillomavirus 1 Infection
por: Jiang, Rosie T., et al.
Publicado: (2017)

Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies
por: Kuriakose Gift, Syna, et al.
Publicado: (2023)

Herpes Simplex Virus 1 Targets the Murine Olfactory Neuroepithelium for Host Entry
por: Shivkumar, Maitreyi, et al.
Publicado: (2013)

Expression of HIV-1 Intron-Containing RNA in Microglia Induces Inflammatory Responses
por: Akiyama, Hisashi, et al.
Publicado: (2021)

HIV-Infected Macrophages Are Infected and Killed by the Interferon-Sensitive Rhabdovirus MG1
por: Sandstrom, Teslin S., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f63mcnn9mt0ogn5csh3v68g8s7