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Structure-Guided Functional Annotation of the Influenza A Virus NS1 Protein Reveals Dynamic Evolution of the p85β-Binding Site during Circulation in Humans

Rational characterization of virulence and host-adaptive markers in the multifunctional influenza A virus NS1 protein is hindered by a lack of comprehensive knowledge about NS1-host protein protein interfaces. Here, we surveyed the impact of amino acid variation in NS1 at its structurally defined bi...

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Detalles Bibliográficos
Autores principales:	Lopes, Antonio M., Domingues, Patricia, Zell, Roland, Hale, Benjamin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640874/ https://www.ncbi.nlm.nih.gov/pubmed/28814525 http://dx.doi.org/10.1128/JVI.01081-17

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