p40(phox)-Deficient Mice Exhibit Impaired Bacterial Clearance and Enhanced Pro-inflammatory Responses during Salmonella enterica serovar Typhimurium Infection

Salmonella enterica serovar Typhimurium (S. Typhimurium) is a major cause of acute gastroenteritis in humans. During infection, reactive oxygen species (ROS), generated from NADPH oxidase (a multisubunit enzyme complex), are required for pathogen killing upon phagocytosis and for regulating pro-infl...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yali, Lv, Meili, Su, Chienwen, Long, Shaorong, Zhang, Wei, Conway, Kara L., Li, Weifen, Xavier, Ramnik J., Shi, Hai Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640886/
https://www.ncbi.nlm.nih.gov/pubmed/29062317
http://dx.doi.org/10.3389/fimmu.2017.01270

Ejemplares similares

Ejemplares similares