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Long-term feeding of high-fat plus high-fructose diet induces isolated impaired glucose tolerance and skeletal muscle insulin resistance in miniature pigs

BACKGROUND: During the prediabetic development, the changes in β-cell function and tissue-specific insulin resistance have been described. However, there are conflicting views in insulin secretory capacity between early clinical observation and recent proposed mathematical model. On the basis of dig...

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Detalles Bibliográficos
Autores principales:	Hsu, Meng-Chieh, Wang, Mu-En, Jiang, Yi-Fan, Liu, Hung-Chang, Chen, Yi-Chen, Chiu, Chih-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640912/ https://www.ncbi.nlm.nih.gov/pubmed/29046729 http://dx.doi.org/10.1186/s13098-017-0281-6

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