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Breast carcinomas with low amplified/equivocal HER2 by Ish: potential supporting role of multiplex ligation-dependent probe amplification

BACKGROUND: This is a retrospective cross sectional study aimed to verify whether Multiplex Ligation-dependent Probe Amplification (MLPA), a quantitative molecular assay, may represent a valuable reflex test in breast cancer with equivocal HER2 expression by immunohistochemistry and HER2 gene signal...

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Detalles Bibliográficos
Autores principales: Ercolani, Cristiana, Marchiò, Caterina, Di Benedetto, Anna, Fabi, Alessandra, Perracchio, Letizia, Vici, Patrizia, Sperati, Francesca, Buglioni, Simonetta, Arena, Vincenzo, Pescarmona, Edoardo, Sapino, Anna, Terrenato, Irene, Mottolese, Marcella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640946/
https://www.ncbi.nlm.nih.gov/pubmed/29029640
http://dx.doi.org/10.1186/s13046-017-0613-2