Fenofibrate decreases the bone quality by down regulating Runx2 in high-fat-diet induced Type 2 diabetes mellitus mouse model

BACKGROUND: This study is to investigate the effect of fenofibrate on the bone quality of Type 2 diabetes mellitus (T2DM) mouse model. METHODS: T2DM mouse model was induced by high-fat-diet, and the mice were treated with fenofibrate (100 mg/kg) (DIO-FENO) or PBS (DIO-PBS) for 4 weeks. The bone micr...

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Detalles Bibliográficos
Autores principales: Shi, Tianshu, Lu, Ke, Shen, Siyu, Tang, Qiaoli, Zhang, Kaijia, Zhu, Xiaobo, Shi, Yong, Liu, Xianglin, Teng, Huajian, Li, Chaojun, Xue, Bin, Jiang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640963/
https://www.ncbi.nlm.nih.gov/pubmed/29029615
http://dx.doi.org/10.1186/s12944-017-0592-5

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