Repurposing Albendazole: new potential as a chemotherapeutic agent with preferential activity against HPV-negative head and neck squamous cell cancer

Albendazole is an anti-helminthic drug that has been shown to exhibit anti-cancer properties, however its activity in head and neck squamous cell cancer (HNSCC) was unknown. Using a series of in vitro assays, we assessed the ability of albendazole to inhibit proliferation in 20 HNSCC cell lines acro...

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Detalles Bibliográficos
Autores principales: Ghasemi, Farhad, Black, Morgan, Vizeacoumar, Frederick, Pinto, Nicole, Ruicci, Kara M., Le, Carson Cao Son Huu, Lowerison, Matthew R., Leong, Hon Sing, Yoo, John, Fung, Kevin, MacNeil, Danielle, Palma, David A., Winquist, Eric, Mymryk, Joe S., Boutros, Paul C., Datti, Alessandro, Barrett, John W., Nichols, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641066/
https://www.ncbi.nlm.nih.gov/pubmed/29069723
http://dx.doi.org/10.18632/oncotarget.17292

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