TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines

Microtubules are cellular targets for a variety of anticancer therapies because of their critical function in mitosis. Taxol belongs to a class of microtubule targeting agents that suppresses microtubule dynamics and interferes with the functioning of the mitotic spindle, thereby effectively blockin...

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Detalles Bibliográficos
Autores principales: Tame, Mihoko A., Manjón, Anna G., Belokhvostova, Daria, Raaijmakers, Jonne A., Medema, René H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641069/
https://www.ncbi.nlm.nih.gov/pubmed/29069726
http://dx.doi.org/10.18632/oncotarget.17740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641069/
https://www.ncbi.nlm.nih.gov/pubmed/29069726
http://dx.doi.org/10.18632/oncotarget.17740

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