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TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines
Microtubules are cellular targets for a variety of anticancer therapies because of their critical function in mitosis. Taxol belongs to a class of microtubule targeting agents that suppresses microtubule dynamics and interferes with the functioning of the mitotic spindle, thereby effectively blockin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641069/ https://www.ncbi.nlm.nih.gov/pubmed/29069726 http://dx.doi.org/10.18632/oncotarget.17740 |